The first phytochemical report of Galanthus transcaucasicus Fomin
نویسندگان
چکیده
UNLABELLED BACKGROUND AND THE PURPOSE OF STUDY: Galanthus transcaucasicus Fomin (Amaryllidaceae) is an endemic species to the Caucasia and Alborz mountains in Iran which locally named "Gole-Barfi". While there are many reports on pharmacological activities of Galanthus species' alkaloids, there is no report on G. transcaucasicus and this article is the first phytochemical study on this species. METHODS Extracted alkaloids from G. transcaucasicus bulbs were isolated using different chromatographic methods and the structures of the components were determined by physical and spectroscopic data. RESULTS Five isoquinoline type alkaloids namely galanthamine (8.04%), narwedine (6.90%), lycorine (19.48%), caranine (3.45%) and tazettine (5.75%) of total alkaloid extract were isolated from the bulbs of Galanthus transcaucasicus Fomin. MAJOR CONCLUSION Because of the presence of biologically active alkaloids especially galanthamine and the major alkaloid lycorine in Gol-e-Barfi, the plant may be used as a natural source for pharmaceutical purposes.
منابع مشابه
Nerinine and homolycorine, amaryllidaceae alkaloids from the bulbs of Galanthus transcaucasicus Fomin
Background and objectives: Many members of the Amaryllidaceae are regarded as toxic. The toxic constituents that occur in the whole family are referred to as the Amaryllidaceae alkaloids. The main aim of this study was the identification of alkaloid compounds from Galanthus transcaucasicus Fomin, a medicinal plant from Amaryllidaceae. Methods: Planar a...
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متن کاملNerinine and homolycorine, amaryllidaceae alkaloids from the bulbs of Galanthus transcaucasicus Fomin
Background and objectives: Many members of the Amaryllidaceae are regarded as toxic. The toxic constituents that occur in the whole family are referred to as the Amaryllidaceae alkaloids. The main aim of this study was the identification of alkaloid compounds from Galanthus transcaucasicus Fomin, a medicinal plant from Amaryllidaceae. Methods: Planar and column chromatography techniques were us...
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